The current Lexus IS covers up to 1,375 km on a full tank, based on combined-cycle consumption. Figures below are the best-range variant in each generation.
| Years | Powertrain | Range |
|---|---|---|
| 1999–2005 | Combustion | 722 |
| 2001–2005 | Combustion | 714 |
| 2005–2009 | Combustion | 1,032 |
| 2009–2013 | Combustion | 1,275 |
| 2017–2021 | Combustion | 1,375 |
Range is calculated from each variant’s fuel tank capacity and combined-cycle consumption (tank ÷ consumption × 100), for the best-range variant in each generation — real-world range varies with driving style and conditions. Figures outside a plausible range for the tank size are excluded.