The current Lexus SC covers up to 625 km on a full tank, based on combined-cycle consumption. Figures below are the best-range variant in each generation.
| Years | Powertrain | Range |
|---|---|---|
| 2001–2010 | Combustion | 625 |
Range is calculated from each variant’s fuel tank capacity and combined-cycle consumption (tank ÷ consumption × 100), for the best-range variant in each generation — real-world range varies with driving style and conditions. Figures outside a plausible range for the tank size are excluded.