The Mercedes-Benz CLS C218 (2010-2014) was offered with 12 distinct engine configurations across its trim range.
| Engine | Power | Torque | Transmission | Drive | Top speed | 0-100 km/h | Consumption | Available on |
|---|---|---|---|---|---|---|---|---|
| 5.5L Petrol | 585 hp | 800 Nm | Automatic | All Wheel Drive | 250 km/h | 3.6 s | 10.4 l/100km | 1 trim |
| 5.5L Petrol | 558 hp | 720 Nm | Automatic | All Wheel Drive | 250 km/h | 3.7 s | 10.4 l/100km | 1 trim |
| 5.5L Petrol | 558 hp | 720 Nm | Automatic | Rear Wheel Drive | 250 km/h | 4.2 s | 9.9 l/100km | 1 trim |
| 5.5L Petrol | 525 hp | 700 Nm | Automatic | Rear Wheel Drive | 250 km/h | 4.4 s | 9.9 l/100km | 1 trim |
| 4.7L Petrol | 408 hp | 600 Nm | Automatic | All Wheel Drive | 250 km/h | 5.2 s | 9.6 l/100km | 1 trim |
| 4.7L Petrol | 408 hp | 600 Nm | Automatic | Rear Wheel Drive | 250 km/h | 5.2 s | 9.0 l/100km | 1 trim |
| 3.5L Petrol | 306 hp | 370 Nm | Automatic | Rear Wheel Drive | 250 km/h | 6.1 s | 6.8 l/100km | 1 trim |
| 3.0L Diesel | 265 hp | 620 Nm | Automatic | All Wheel Drive | 250 km/h | 6.4 s | 6.7 l/100km | 1 trim |
| 3.0L Diesel | 265 hp | 620 Nm | Automatic | Rear Wheel Drive | 250 km/h | 6.2 s | 6.0 l/100km | 1 trim |
| 3.0L Diesel | 252 hp | 620 Nm | Automatic | All Wheel Drive | 245 km/h | 6.7 s | 6.1 l/100km | 1 trim |
| 3.0L Diesel | 252 hp | 620 Nm | Automatic | Rear Wheel Drive | 250 km/h | 6.6 s | 5.5 l/100km | 1 trim |
| 2.1L Diesel | 204 hp | 500 Nm | Automatic | Rear Wheel Drive | 242 km/h | 7.5 s | 5.1 l/100km | 1 trim |
Each row is a distinct mechanical configuration — engine size, power output, transmission, drivetrain and fuel type — deduplicated across equipment trims that share the same engine. Trim-only differences (interior, wheels, options) do not create a separate row.