The Mercedes-Benz E-Class Facelift 2020 (2020-2022) was offered with 17 distinct engine configurations across its trim range.
| Engine | Power | Torque | Transmission | Drive | Top speed | 0-100 km/h | Consumption | Available on |
|---|---|---|---|---|---|---|---|---|
| 4.0L Petrol | 612 hp | 850 Nm | Automatic | All Wheel Drive | 250 km/h | 3.4 s | 12.1 l/100km | 1 trim |
| 4.0L Petrol | 571 hp | 750 Nm | Automatic | All Wheel Drive | 250 km/h | 3.5 s | 12.0 l/100km | 1 trim |
| 3.0L Mild Hybrid | 435 hp | 520 Nm | Automatic | All Wheel Drive | 250 km/h | 4.5 s | 9.1 l/100km | 1 trim |
| 3.0L Mild Hybrid | 367 hp | 500 Nm | Automatic | All Wheel Drive | 250 km/h | 5.0 s | 8.2 l/100km | 3 trims |
| 2.9L Diesel | 330 hp | 700 Nm | Automatic | All Wheel Drive | 250 km/h | 4.9 s | 6.6 l/100km | 3 trims |
| 2.0L Mild Hybrid | 265 hp | 550 Nm | Automatic | All Wheel Drive | 250 km/h | 6.3 s | 5.8 l/100km | 1 trim |
| 2.0L Mild Hybrid | 258 hp | 370 Nm | Automatic | Rear Wheel Drive | 250 km/h | 6.2 s | 7.3 l/100km | 1 trim |
| 2.0L Plug-in Hybrid | 211 hp | 350 Nm | Automatic | All Wheel Drive | 250 km/h | 5.7 s | 1.7 l/100km | 3 trims |
| 2.0L Plug-in Hybrid | 211 hp | 350 Nm | Automatic | Rear Wheel Drive | 250 km/h | 5.7 s | 1.6 l/100km | 5 trims |
| 2.0L Mild Hybrid | 200 hp | 440 Nm | Automatic | Rear Wheel Drive | 238 km/h | 7.4 s | 4.8 l/100km | 2 trims |
| 2.0L Mild Hybrid | 197 hp | 320 Nm | Automatic | All Wheel Drive | 232 km/h | 7.6 s | 7.7 l/100km | 1 trim |
| 2.0L Mild Hybrid | 197 hp | 320 Nm | Automatic | Rear Wheel Drive | 240 km/h | 7.5 s | 7.2 l/100km | 6 trims |
| 1.9L Plug-in Hybrid | 194 hp | 400 Nm | Automatic | All Wheel Drive | 235 km/h | 5.9 s | 1.7 l/100km | 3 trims |
| 1.9L Plug-in Hybrid | 194 hp | 400 Nm | Automatic | Rear Wheel Drive | 250 km/h | 5.9 s | 1.2 l/100km | 5 trims |
| 1.9L Diesel | 194 hp | 400 Nm | Automatic | All Wheel Drive | 239 km/h | 7.5 s | 5.6 l/100km | 1 trim |
| 1.9L Diesel | 194 hp | 400 Nm | Automatic | Rear Wheel Drive | 240 km/h | 7.3 s | 5.3 l/100km | 1 trim |
| 1.6L Diesel | 160 hp | 360 Nm | Automatic | Rear Wheel Drive | 226 km/h | 8.4 s | 4.9 l/100km | 6 trims |
Each row is a distinct mechanical configuration — engine size, power output, transmission, drivetrain and fuel type — deduplicated across equipment trims that share the same engine. Trim-only differences (interior, wheels, options) do not create a separate row.