The Mercedes-Benz S-Class Facelift 2017 (2017-2020) was offered with 12 distinct engine configurations across its trim range.
| Engine | Power | Torque | Transmission | Drive | Top speed | 0-100 km/h | Consumption | Available on |
|---|---|---|---|---|---|---|---|---|
| 6.0L Petrol | 630 hp | 1,000 Nm | Automatic | All Wheel Drive | 250 km/h | 4.3 s | 14.2 l/100km | 2 trims |
| 4.0L Petrol | 612 hp | 900 Nm | Automatic | All Wheel Drive | 250 km/h | 3.5 s | 11.2 l/100km | 1 trim |
| 6.0L Petrol | 530 hp | 830 Nm | Automatic | Rear Wheel Drive | 250 km/h | 4.6 s | 14.0 l/100km | 1 trim |
| 4.0L Petrol | 469 hp | 700 Nm | Automatic | All Wheel Drive | 250 km/h | 4.9 s | 10.3 l/100km | 4 trims |
| 4.0L Petrol | 469 hp | 700 Nm | Automatic | Rear Wheel Drive | 250 km/h | 4.9 s | 10.1 l/100km | 2 trims |
| 3.0L Petrol | 367 hp | 500 Nm | Automatic | All Wheel Drive | 250 km/h | 5.0 s | 2.8 l/100km | 1 trim |
| 3.0L Petrol | 367 hp | 500 Nm | Automatic | All Wheel Drive | 250 km/h | 4.9 s | 8.1 l/100km | 2 trims |
| 3.0L Petrol | 367 hp | 500 Nm | Automatic | Rear Wheel Drive | 250 km/h | 5.1 s | 7.3 l/100km | 2 trims |
| 2.9L Diesel | 340 hp | 700 Nm | Automatic | All Wheel Drive | 250 km/h | 5.2 s | 6.2 l/100km | 2 trims |
| 2.9L Diesel | 340 hp | 700 Nm | Automatic | Rear Wheel Drive | 250 km/h | 5.4 s | 5.9 l/100km | 2 trims |
| 2.9L Diesel | 286 hp | 600 Nm | Automatic | All Wheel Drive | 250 km/h | 5.8 s | 6.2 l/100km | 2 trims |
| 2.9L Diesel | 286 hp | 600 Nm | Automatic | Rear Wheel Drive | 250 km/h | 6.0 s | 5.9 l/100km | 2 trims |
Each row is a distinct mechanical configuration — engine size, power output, transmission, drivetrain and fuel type — deduplicated across equipment trims that share the same engine. Trim-only differences (interior, wheels, options) do not create a separate row.