Mercedes-Benz · S-Class · S-Class W221 (2005-2009)

Mercedes-Benz S-Class S 350 4Matic

SedanPetrolAutomaticAWDYear 2008G
272
Horsepower · 200 kW
7.3s
0–100 km/h
250
km/h top speed
10.6
l/100 km

The Mercedes-Benz S-Class S 350 4Matic is a sedan powered by a petrol engine delivering 272 hp (200 kW). It accelerates from 0 to 100 km/h in 7.3 s and reaches a top speed of 250 km/h. Fuel efficiency stands at 10.6 l/100 km combined, CO₂ emissions of 254 g/km. Drive is routed to the all-wheel-drive axle via an automatic. This variant was introduced in 2008 as part of the Mercedes-Benz S-Class W221 (2005-2009) generation, and sits alongside 3 other variants in this generation. Full specifications — including engine displacement, transmission type, dimensions, weight, and historical list price — are available on the specifications page.

Updated Jun 2026 · Data curated by Cars-Data.com
Quick answers
What is the engine power of the Mercedes-Benz S-Class S 350 4Matic?

The Mercedes-Benz S-Class S 350 4Matic produces 272 hp (200 kW).

How fast does the Mercedes-Benz S-Class S 350 4Matic accelerate from 0 to 100 km/h?

The Mercedes-Benz S-Class S 350 4Matic accelerates from 0 to 100 km/h in 7.3 seconds.

What is the top speed of the Mercedes-Benz S-Class S 350 4Matic?

The top speed of the Mercedes-Benz S-Class S 350 4Matic is 250 km/h.

What is the fuel consumption of the Mercedes-Benz S-Class S 350 4Matic?

The Mercedes-Benz S-Class S 350 4Matic has a combined fuel consumption of 10.6 l/100 km.

What are the CO₂ emissions of the Mercedes-Benz S-Class S 350 4Matic?

The Mercedes-Benz S-Class S 350 4Matic emits 254 g/km of CO₂.

What transmission does the Mercedes-Benz S-Class S 350 4Matic have?

The Mercedes-Benz S-Class S 350 4Matic is equipped with a Automatic transmission.

Is the Mercedes-Benz S-Class S 350 4Matic front, rear, or all-wheel drive?

The Mercedes-Benz S-Class S 350 4Matic sends power through the ALL WHEEL DRIVE drivetrain.

What is the engine size of the Mercedes-Benz S-Class S 350 4Matic?

The Mercedes-Benz S-Class S 350 4Matic has a 3,498 cc engine with 6 cylinders.

What is the torque of the Mercedes-Benz S-Class S 350 4Matic?

The Mercedes-Benz S-Class S 350 4Matic produces 350 Nm of torque.

When was the Mercedes-Benz S-Class S 350 4Matic introduced?

The Mercedes-Benz S-Class S 350 4Matic was introduced in 2008.