Mercedes-Benz S-Class W221
The Mercedes-Benz S-Class W221 is a sedan, produced 2005–2009. This generation includes 54 variants available in Petrol and Diesel, with outputs ranging from 235 to 612 hp. The quickest variant in this generation reaches 100 km/h in 4.4 seconds. Drive configurations available include REAR WHEEL DRIVE and ALL WHEEL DRIVE. Select a variant below to compare full specifications, or use the fuel filter to narrow the list by powertrain type.
Mercedes-Benz S-Class W221 — 54 variants
Quick answers
What body type is the Mercedes-Benz S-Class W221 (2005-2009)?
The Mercedes-Benz S-Class W221 (2005-2009) is a sedan. All 54 variants in this generation share this body configuration. Full specifications including dimensions, weight, and cargo volume are listed on each variant page.
How many variants does the Mercedes-Benz S-Class W221 (2005-2009) have?
The Mercedes-Benz S-Class W221 (2005-2009) has 54 variants, each representing a distinct combination of engine output, transmission type, and equipment level. Browse the table below to compare power, acceleration, and consumption across all specs.
What years was the Mercedes-Benz S-Class W221 (2005-2009) produced?
The Mercedes-Benz S-Class W221 (2005-2009) was produced 2005–2009. During this production run the model was offered with multiple engine options and powertrain configurations. All variants from this period remain indexed with their original manufacturer specifications.
What fuel types are available in the Mercedes-Benz S-Class W221 (2005-2009)?
The Mercedes-Benz S-Class W221 (2005-2009) is available in Petrol, Diesel. Each fuel variant carries its own consumption rating, CO₂ output, and performance figures. Use the fuel filter above to narrow the list by powertrain type.