14 de 14 variantes tienen datos de top speed.
| Variante | Año | Carrocería | Combustible | Top speed |
|---|---|---|---|---|
| Chrysler 300C Touring HEMI 6.1 V8 SRT8 | 2006 | Familiar | Gasolina | 265 km/h |
| Chrysler 300C HEMI 6.1 V8 SRT8 | 2006 | Sedán | Gasolina | 265 km/h |
| Chrysler 300C Touring HEMI 5.7 V8 | 2004 | Familiar | Gasolina | 250 km/h |
| Chrysler 300C Touring HEMI 5.7 V8 AWD | 2004 | Familiar | Gasolina | 250 km/h |
| Chrysler 300C HEMI 5.7 V8 | 2004 | Sedán | Gasolina | 250 km/h |
| Chrysler 300C 3.0 CRD Signature Series | 2010 | Sedán | Diésel | 230 km/h |
| Chrysler 300C 3.0 CRD | 2005 | Sedán | Diésel | 230 km/h |
| Chrysler 300C Touring 3.0 CRD Signature Series | 2010 | Familiar | Diésel | 227 km/h |
| Chrysler 300C Touring 3.0 CRD | 2005 | Familiar | Diésel | 227 km/h |
| Chrysler 300C Touring 3.5 V6 | 2004 | Familiar | Gasolina | 219 km/h |
| Chrysler 300C Touring 3.5 V6 AWD | 2004 | Familiar | Gasolina | 219 km/h |
| Chrysler 300C 3.5 V6 | 2004 | Sedán | Gasolina | 219 km/h |
| Chrysler 300C Touring 2.7 V6 | 2004 | Familiar | Gasolina | 209 km/h |
| Chrysler 300C 2.7 V6 | 2004 | Sedán | Gasolina | 209 km/h |