La Mercedes-Benz E-Class Facelift 1999 (1999-2002) a été proposée avec 21 configurations moteur distinctes sur l’ensemble de ses finitions.
| Moteur | Puissance | Couple | Transmission | Roues motrices | Vitesse maximale | 0-100 km/h | Consommation | Disponible sur |
|---|---|---|---|---|---|---|---|---|
| 5.4L Essence | 354 hp | 530 Nm | Automatic | Rear Wheel Drive | 250 km/h | 5.7 s | 12.1 l/100km | 1 finition |
| 4.3L Essence | 279 hp | 400 Nm | Automatic | All Wheel Drive | 250 km/h | 6.8 s | 12.3 l/100km | 4 finitions |
| 4.3L Essence | 279 hp | 400 Nm | Automatic | Rear Wheel Drive | 250 km/h | 6.6 s | 10.8 l/100km | 4 finitions |
| 3.2L Essence | 224 hp | 315 Nm | Automatic | All Wheel Drive | 230 km/h | 8.3 s | 11.1 l/100km | 5 finitions |
| 3.2L Essence | 224 hp | 315 Nm | Automatic | Rear Wheel Drive | 238 km/h | 7.9 s | 10.3 l/100km | 5 finitions |
| 2.8L Essence | 204 hp | 270 Nm | Automatic | All Wheel Drive | 223 km/h | 9.4 s | 11.2 l/100km | 5 finitions |
| 2.8L Essence | 204 hp | 270 Nm | Automatic | Rear Wheel Drive | 230 km/h | 9.1 s | 10.7 l/100km | 5 finitions |
| 2.8L Essence | 204 hp | 270 Nm | Manual | Rear Wheel Drive | 230 km/h | 8.9 s | 10.8 l/100km | 1 finition |
| 3.2L Diesel | 197 hp | 470 Nm | Automatic | Rear Wheel Drive | 230 km/h | 8.3 s | 7.8 l/100km | 5 finitions |
| 2.7L Diesel | 170 hp | 400 Nm | Automatic | Rear Wheel Drive | 220 km/h | 9.3 s | 7.2 l/100km | 5 finitions |
| 2.7L Diesel | 170 hp | 370 Nm | Manual | Rear Wheel Drive | 225 km/h | 9.0 s | 6.9 l/100km | 1 finition |
| 2.4L Essence | 170 hp | 225 Nm | Automatic | Rear Wheel Drive | 222 km/h | 10.8 s | 10.3 l/100km | 5 finitions |
| 2.4L Essence | 170 hp | 225 Nm | Manual | Rear Wheel Drive | 224 km/h | 9.8 s | 10.8 l/100km | 1 finition |
| 2.0L Essence | 163 hp | 230 Nm | Automatic | Rear Wheel Drive | 219 km/h | 10.2 s | 9.6 l/100km | 5 finitions |
| 2.0L Essence | 163 hp | 230 Nm | Manual | Rear Wheel Drive | 222 km/h | 9.7 s | 8.9 l/100km | 1 finition |
| 2.1L Diesel | 143 hp | 315 Nm | Automatic | Rear Wheel Drive | 212 km/h | 10.7 s | 6.7 l/100km | 5 finitions |
| 2.1L Diesel | 143 hp | 315 Nm | Manual | Rear Wheel Drive | 213 km/h | 10.4 s | 6.2 l/100km | 1 finition |
| 2.0L Essence | 136 hp | 190 Nm | Automatic | Rear Wheel Drive | 202 km/h | 12.3 s | 9.6 l/100km | 3 finitions |
| 2.0L Essence | 136 hp | 190 Nm | Manual | Rear Wheel Drive | 209 km/h | 10.8 s | 9.3 l/100km | 1 finition |
| 2.1L Diesel | 115 hp | 250 Nm | Automatic | Rear Wheel Drive | 197 km/h | 12.5 s | 6.7 l/100km | 5 finitions |
| 2.1L Diesel | 115 hp | 250 Nm | Manual | Rear Wheel Drive | 199 km/h | 12.5 s | 6.2 l/100km | 1 finition |
Chaque ligne est une configuration mécanique distincte — cylindrée, puissance, transmission, roues motrices et type de carburant — dédupliquée entre les finitions qui partagent le même moteur. Les différences de finition seules (intérieur, jantes, options) ne créent pas de ligne séparée.