Mercedes-Benz E-Class Combi (1999–2002) nudio se s 19 različitih konfiguracija motora kroz cijelu ponudu opreme.
| Motor | Snaga | Okretni moment | Mjenjač | Pogon | Najveća brzina | 0-100 km/h | Potrošnja | Dostupno u |
|---|---|---|---|---|---|---|---|---|
| 5.4L Benzin | 354 hp | 530 Nm | Automatic | Rear Wheel Drive | 250 km/h | 5.9 s | 12.6 l/100km | 1 verziji |
| 4.3L Benzin | 279 hp | 400 Nm | Automatic | All Wheel Drive | 250 km/h | 7.2 s | 12.9 l/100km | 4 verzije |
| 4.3L Benzin | 279 hp | 400 Nm | Automatic | Rear Wheel Drive | 243 km/h | 6.9 s | 11.4 l/100km | 4 verzije |
| 3.2L Benzin | 224 hp | 315 Nm | Automatic | All Wheel Drive | 225 km/h | 9.2 s | 11.5 l/100km | 5 verzija |
| 3.2L Benzin | 224 hp | 315 Nm | Automatic | Rear Wheel Drive | 230 km/h | 8.7 s | 10.6 l/100km | 5 verzija |
| 2.8L Benzin | 204 hp | 270 Nm | Automatic | All Wheel Drive | 217 km/h | 10.2 s | 11.5 l/100km | 5 verzija |
| 2.8L Benzin | 204 hp | 270 Nm | Automatic | Rear Wheel Drive | 223 km/h | 9.5 s | 11.2 l/100km | 5 verzija |
| 2.8L Benzin | 204 hp | 270 Nm | Manual | Rear Wheel Drive | 225 km/h | 9.5 s | 11.3 l/100km | 1 verziji |
| 3.2L Dizel | 197 hp | 470 Nm | Automatic | Rear Wheel Drive | 227 km/h | 8.8 s | 7.9 l/100km | 5 verzija |
| 2.7L Dizel | 170 hp | 400 Nm | Automatic | Rear Wheel Drive | 212 km/h | 9.8 s | 7.3 l/100km | 5 verzija |
| 2.7L Dizel | 170 hp | 370 Nm | Manual | Rear Wheel Drive | 215 km/h | 9.5 s | 7.1 l/100km | 1 verziji |
| 2.4L Benzin | 170 hp | 225 Nm | Automatic | Rear Wheel Drive | 212 km/h | 11.4 s | 10.9 l/100km | 5 verzija |
| 2.4L Benzin | 170 hp | 225 Nm | Manual | Rear Wheel Drive | 215 km/h | 10.7 s | 11.2 l/100km | 1 verziji |
| 2.0L Benzin | 163 hp | 230 Nm | Automatic | Rear Wheel Drive | 209 km/h | 10.7 s | 9.8 l/100km | 5 verzija |
| 2.0L Benzin | 163 hp | 230 Nm | Manual | Rear Wheel Drive | 212 km/h | 10.1 s | 9.3 l/100km | 1 verziji |
| 2.1L Dizel | 143 hp | 315 Nm | Automatic | Rear Wheel Drive | 202 km/h | 11.2 s | 7.1 l/100km | 5 verzija |
| 2.1L Dizel | 143 hp | 315 Nm | Manual | Rear Wheel Drive | 205 km/h | 10.9 s | 6.8 l/100km | 1 verziji |
| 2.0L Benzin | 136 hp | 190 Nm | Automatic | Rear Wheel Drive | 195 km/h | 13.1 s | 9.9 l/100km | 3 verzije |
| 2.0L Benzin | 136 hp | 190 Nm | Manual | Rear Wheel Drive | 198 km/h | 11.0 s | 9.6 l/100km | 1 verziji |
Svaki je red zasebna mehanička konfiguracija — obujam motora, snaga, mjenjač, pogon i vrsta goriva — deduplicirana kroz razine opreme koje dijele isti motor. Razlike samo u opremi (unutrašnjost, naplatci, opcije) ne stvaraju zaseban red.