Mercedes-Benz E-Class Facelift 1999 (1999-2002) nuđen je sa 21 različitih konfiguracija motora kroz celu ponudu opreme.
| Motor | Snaga | Obrtni moment | Menjač | Pogon | Najveća brzina | 0-100 km/h | Potrošnja | Dostupno u |
|---|---|---|---|---|---|---|---|---|
| 5.4L Benzin | 354 hp | 530 Nm | Automatic | Rear Wheel Drive | 250 km/h | 5.7 s | 12.1 l/100km | 1 verziji |
| 4.3L Benzin | 279 hp | 400 Nm | Automatic | All Wheel Drive | 250 km/h | 6.8 s | 12.3 l/100km | 4 verzije |
| 4.3L Benzin | 279 hp | 400 Nm | Automatic | Rear Wheel Drive | 250 km/h | 6.6 s | 10.8 l/100km | 4 verzije |
| 3.2L Benzin | 224 hp | 315 Nm | Automatic | All Wheel Drive | 230 km/h | 8.3 s | 11.1 l/100km | 5 verzija |
| 3.2L Benzin | 224 hp | 315 Nm | Automatic | Rear Wheel Drive | 238 km/h | 7.9 s | 10.3 l/100km | 5 verzija |
| 2.8L Benzin | 204 hp | 270 Nm | Automatic | All Wheel Drive | 223 km/h | 9.4 s | 11.2 l/100km | 5 verzija |
| 2.8L Benzin | 204 hp | 270 Nm | Automatic | Rear Wheel Drive | 230 km/h | 9.1 s | 10.7 l/100km | 5 verzija |
| 2.8L Benzin | 204 hp | 270 Nm | Manual | Rear Wheel Drive | 230 km/h | 8.9 s | 10.8 l/100km | 1 verziji |
| 3.2L Dizel | 197 hp | 470 Nm | Automatic | Rear Wheel Drive | 230 km/h | 8.3 s | 7.8 l/100km | 5 verzija |
| 2.7L Dizel | 170 hp | 400 Nm | Automatic | Rear Wheel Drive | 220 km/h | 9.3 s | 7.2 l/100km | 5 verzija |
| 2.7L Dizel | 170 hp | 370 Nm | Manual | Rear Wheel Drive | 225 km/h | 9.0 s | 6.9 l/100km | 1 verziji |
| 2.4L Benzin | 170 hp | 225 Nm | Automatic | Rear Wheel Drive | 222 km/h | 10.8 s | 10.3 l/100km | 5 verzija |
| 2.4L Benzin | 170 hp | 225 Nm | Manual | Rear Wheel Drive | 224 km/h | 9.8 s | 10.8 l/100km | 1 verziji |
| 2.0L Benzin | 163 hp | 230 Nm | Automatic | Rear Wheel Drive | 219 km/h | 10.2 s | 9.6 l/100km | 5 verzija |
| 2.0L Benzin | 163 hp | 230 Nm | Manual | Rear Wheel Drive | 222 km/h | 9.7 s | 8.9 l/100km | 1 verziji |
| 2.1L Dizel | 143 hp | 315 Nm | Automatic | Rear Wheel Drive | 212 km/h | 10.7 s | 6.7 l/100km | 5 verzija |
| 2.1L Dizel | 143 hp | 315 Nm | Manual | Rear Wheel Drive | 213 km/h | 10.4 s | 6.2 l/100km | 1 verziji |
| 2.0L Benzin | 136 hp | 190 Nm | Automatic | Rear Wheel Drive | 202 km/h | 12.3 s | 9.6 l/100km | 3 verzije |
| 2.0L Benzin | 136 hp | 190 Nm | Manual | Rear Wheel Drive | 209 km/h | 10.8 s | 9.3 l/100km | 1 verziji |
| 2.1L Dizel | 115 hp | 250 Nm | Automatic | Rear Wheel Drive | 197 km/h | 12.5 s | 6.7 l/100km | 5 verzija |
| 2.1L Dizel | 115 hp | 250 Nm | Manual | Rear Wheel Drive | 199 km/h | 12.5 s | 6.2 l/100km | 1 verziji |
Svaki red je zasebna mehanička konfiguracija — zapremina motora, snaga, menjač, pogon i vrsta goriva — deduplikovana kroz nivoe opreme koji dele isti motor. Razlike samo u opremi (enterijer, felne, opcije) ne stvaraju poseban red.